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$27 Million Grant Focuses on the Future of Biomanufacturing

A new 5-year project led by North Carolina State University will sponsor an international collaborative research and training program in biomanufacturing science and technology.
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Transplanted Brain Stem Cells Survive in Mice Without Anti-rejection Drugs

In experiments in mice, Johns Hopkins Medicine researchers have developed a way to successfully transplant certain protective brain cells without the need for lifelong anti-rejection drugs.
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Discontinuing Oral Immunotherapy for Peanut Allergy Reduces Its Protective Effects

A study has followed participants after oral immunotherapy (OIT) for peanut allergy have found that discontinuing OIT or continuing OIT at a reduced dose led to a decline in its protective effects.
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Knotty Problem of Cell Reprogramming Solved

Researchers have found a way to repurpose cells more reliably than current methods by untangling DNA, clearing a roadblock in regenerative medicine to reach treatments for a wide range of diseases.
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B Cells May Be More Important in Immunotherapy Than Previously Thought

Researchers have found evidence that B cells might play an important role in immunotherapy for melanoma. Currently, immunotherapy is primarily focused on T cells, but the results suggest that B cells could also provide an interesting research avenue.
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Novel Gene Therapy Is Successful in Improving Functional Recovery After Stroke

In a mouse model of stroke, researchers successfully pioneer a new gene therapy developed to turn glial cells into neurons.
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Vanquishing Malaria With a Sponge?

Current medications for malaria are becoming less effective as drug resistance spreads, but the frigid waters of the Antarctic may yield a treatment.
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First-of-Its-Kind Study Shows CAR-T Cell Therapy May Be Viable for Heart Disease Treatment

In a world first, researchers from Penn Medicine have used genetically modified T cells to target and ablate fibroblasts that contribute to the development of heart disease.
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The Impact of Age on Immunotherapy Treatment for Breast Cancer

To understand the influence of aging on the effectiveness of immune checkpoint blockade (ICB) therapy, researchers conducted preclinical studies using younger and older mice with triple negative breast cancer, finding that age affects the efficacy of ICB therapy.
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Flu Vaccine Effectiveness May Be Impacted by Microbiome Disruption

Oral antibiotics, which can kill gut microorganisms, can alter the human immune response to seasonal influenza vaccination.
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