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A study in mice reveals that the intestine maximizes nutrient uptake while protecting the body from potentially dangerous invading microbes, two seemingly conflicting functions. The research has potential to improve drugs for gastrointestinal disorders, as well as inform the development of oral vaccines.

Researchers have revealed that a protein called membralin plays a key role in ALS and identified a membralin-boosting gene therapy that extended the survival of mice with ALS-like symptoms.

By using quantitative lineage-tracing approaches, cells of the mouse intestinal epithelium were shown to contribute actively to the adult intestinal stem cell pool, regardless of their location and pattern of LGR5 expression in the fetal gut tube.

Charcot-Leyden Crystals are made from the protein Galectin-10 and were discovered in the airways of asthmatics as early as 1853. However, the crystals have been largely ignored by scientists, and their actual link to disease remained unknown, until now.

While many regenerative medicine applications are being pursued, the ability to track cells after transplant and determine their therapeutic efficacy is a challenge. Could exosomes, circulating cell-derived vesicles, hold the key?

Mitochondria, the "batteries" that produce our energy, interact with the cell’s nucleus in subtle ways previously unseen in humans, according to research published today in the journal Science.

Learning first-hand of the pain and cost of vaccine-preventable diseases moves the needle.

A certain group of cancer drugs (MEK Inhibitors) activate the cancer-promoting Wnt signaling pathway in colorectal cancer cells. The findings suggest a possible explanation for why these drugs are not effective in colorectal cancer.

A study of nearly 300 patients with mild persistent asthma found that inhaled steroids—long considered the gold standard for asthma treatment—were no more effective than placebo in nearly 75 % of the study patients.

Researchers have shown that when honey from strawberry trees is added to colon cancer cells grown in the laboratory, cell proliferation is stopped.