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Squishing Blood Stem Cells Could Facilitate Harvest for Transplants
Modulating blood-forming stem cells’ stiffness could possibly facilitate mobilization procedures used for stem cell-based transplants. Temporary squishiness could help drive blood-forming stem cells out of the bone marrow and into the blood.
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Topical Immunotherapy Lowers Risk of Skin Cancer
A combination of two topical creams already shown to clear precancerous skin lesions from sun-damaged skin also lowers the risk that patients will later develop squamous cell carcinoma of the skin.
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Bacteria Bide Their Time When Antibiotics Attack
If an antibiotic doesn’t kill all the bacteria that infects a patient, the surviving bugs may be particularly adept at timing their resurgence.
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Tissue-engineering Approach for Common Jaw Defect
Cells were taken from rib cartilage of a Yucatan miniature pig, grown in a laboratory and implanted as a construct into a separate animal.
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Antibodies Stabilize Plaque in Arteries
An unexpected role for type IgG antibodies has been identified, after a study in mice showed that the antibodies stabilize the plaque that accumulates on the artery walls, reducing the risk of rupture and blood clot.
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Microbe Motility Enhanced by Microbiome Metabolites in Colon Chip
By leveraging an organ-on-a-chip model and a bioreactor, four human gut metabolites have been identified that can help explain the enhanced sensitivity of the human colon towards enterohemorrhagic E. coli, which is responsible for more than 100,000 infections per year in the USA alone.
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Substance From Plant Slows Down Aggressive Eye Cancer
An active substance that has been known for 30 years could unexpectedly turn into a ray of hope against eye tumors. The plant leaves of which contain the tested substance is anything but rare: At Christmas time you can find it in every well-assorted garden center.
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Zika Study May "Supercharge" Vaccine Research
Scientists looking at the genetics of Zika virus have found a way to fast-track research which could lead to new vaccines.
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Device Would Allow TB Dosing to Switch From Daily to Monthly
A drug delivery device is under development, which works by slowly releasing antibiotics directly into the patient's stomach. This would allow patients to switch from daily to monthly doses, reducing the burden of tuberculosis treatment.
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From Mirror-image Biology to Enhanced Therapeutic Proteins
Biomolecules are being synthesized in their mirror-image form, as part of a bigger long-term goal: to create simple, artificial biological systems in mirror-image form that correspond to those in nature but do not interact with the environment.
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