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Engineered DNA Vaccine Protects Against Emerging Mayaro Virus Infection
A novel, synthetic DNA vaccine induces protective immunity against Mayaro virus, a mosquito-borne infection endemic to South America, that has the potential to become a global emerging viral threat.
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Genes That Help Harmful Bacteria Thwart Treatment
Researchers at Rutgers University-New Brunswick found the two genes in some strains of S. aureus bacteria. The genes protect the germs from copper, which is increasingly used in the global fight against severe infections.
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Oral Chemotherapy to be Trialed
An experimental chemotherapy drug that can be taken orally is moving into early phase clinical trials.
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Exosome-hacking Boosts Leishmania Infections
The LVR1 virus infects ancient eukaryotes called Leishmania, causing debilitating lesions and ulcers. This study has revealed that viral RNA is exposed to host cells via exosomes, tiny cell-derived vesicles that reside in most bodily fluids.
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Lipid Deposition in Rotator Cuff Injuries
Why are fat deposits more likely to occur after tears of the shoulder’s rotator cuff, compared with other types of muscle injuries?
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Vitamin D Boosts Drug-resistant TB Clearance
Vitamin D has been found to speed up the clearance of tuberculosis (TB) bacteria from the lungs of people with multi-drug resistant TB.
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How Fibrosis Develops in Butterfly Syndrome
Butterfly syndrome is a rare inherited condition that causes the skin to become very fragile, and blister following minor friction. New data points to the major driver of fibrosis in these patients, giving therapeutic research new direction.
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Growth of Kidney Vasculature Compensates After Blockage Removal
Repaired kidneys of newborn mice have demonstrated a remarkable capacity for regeneration, which has potential therapeutic implications for infants, children and adults suffering from chronic kidney disease.
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Miniature Chip Quantifies Cell Survival Much Faster Than Gold Standard
A new toxicity test can measure chemical effects on cell survival with much greater sensitivity than some of the most popular tests used today.
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Spermatogenesis Insights Generate Infertility Therapy Possibilities
Using a leading-edge technique, researchers define the cell types in both newborn and adult human testes, opening a path for new strategies to treat male infertility with stem cells.
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