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Could Gut Microbes from Healthy Infants Treat Milk Allergy?
Gut microbes from healthy human infant donors transplanted into mice protected animals exposed to milk from experiencing allergic reactions.
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Engineered T Cells Promote Long-term Organ Transplant Acceptance
A new molecular approach has been identified which helps prevent rejection of transplanted organs, while simultaneously maintaining the ability to fight against infections.
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Can Fecal Microbiota Transplant Prevent Recurrent Diarrheal Disease?
A clinical trial has begun examining whether fecal microbiota transplantation by enema is safe and can prevent recurrent Clostridium difficile-associated disease, a potentially life-threatening diarrheal illness.
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Adverse Birth Outcomes More Likely in Babies Born from Influenza-infected Women
An assessment of data from babies born from pregnant women with and without 2009 H1N1 influenza infection during pregnancy has revealed fresh insights on the impact on the newborn.
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Osteoarthritis Stem Cell Therapy Success in Phase I and II Trials
Details of a new therapy for the symptomatic treatment of osteoarthritis have been revealed, using mesenchymal cells from umbilical cord stroma.
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VISTA Checkpoint a Potential Pancreatic Cancer Immunotherapy Target
A new potential immunotherapy target has been identified for pancreatic cancer, which so far has been notoriously resistant to treatment with immune checkpoint blockade drugs effective against a variety of other cancers.
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Liver-on-chip Enables Real-time Cholesterol Measurement
A microfluidic liver-on-chip system which enables real-time measurement of cholesterol has been developed to study the effects of potentially cholesterol-lowering drugs in real time.
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Antimicrobial Peptides Freeze Cytoplasmic Motion, Render Bacteria Susceptible to Attack
A previously unknown mechanism has been revealed for LL-37 and similar peptides, which are being tested in early-stage clinical trials for treating infections resistant to classical antibiotics.
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HIV Undetectable Equals Untransmittable
An overwhelming body of clinical evidence has firmly established the HIV Undetectable = Untransmittable (U=U) concept as scientifically sound, providing important guidance for HIV prevention.
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Major Progress for Rare Autoimmune Syndrome Gene Therapy
This gene therapy is similar to the technique the lab has used against another immune disease—severe combined immune deficiency, also known as bubble baby disease.
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