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Bacterial ‘Sleeper Cells’ Evade Antibiotics and Weaken Defence Against Infection
These bacteria persister cells stop replicating and can remain in this dormant, ‘sleeper-cell’ state for days, weeks or even months. When antibiotic treatment has been stopped, if some of these bacterial cells spring back to life, they can trigger another infection.
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From Fibroblast to Antigen-presenting Dendritic Cell: a Pioneering Approach
Direct programming of mouse and human skin cells into antigen-presenting dendritic cells opens up the possibility of developing novel dendritic cell-based immunotherapies against cancer.
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Antibiotics Generated from Wasp Venom
Altered peptides from a South American wasp’s venom can kill bacteria but are nontoxic to human cells.
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The First Organ to be Bioprinted in Space
Russian astronauts onboard a spacecraft have reportedly bioprinted a mouse thyroid. This is definitely a world-first in outer space bioprinting.
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Real-time Flu Tracker Website Launched
Pathologists have developed a real-time website to track flu cases across eight hospitals, just in time to assist physicians, the CDC and patients for the fall 2018 flu season.
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Emerging Strategies for Treating Opioid-use Disorder
Anti-opioid immunopharmacotherapies (e.g., conjugate vaccines) that sequester drug peripherally, preventing opioids from reaching targeted receptors in the brain, have recently emerged as promising therapeutics.
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Cancer Vaccine Progress: Potentially Rich Source of Tumor Specific Antigens Identified
The immunogenicity and efficacy of tumor specific antigen vaccination for select antigens has been validated in mouse models of cancer. The researchers believe that clinical trials for human cancer vaccines could start within the next 2-3 years.
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Zika Vaccine Candidate Effective in Preclinical Trials
Demonstrating the effectiveness of the vaccine candidate in monkeys (non-human primates) is an important milestone because it typically predicts the vaccine will work in humans, enabling further clinical development.
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Honeybee Protein Keeps Stem Cells Youthful
An active protein component of royal jelly helps honeybees create new queens. Stanford researchers have identified a similar protein in mammals, which keeps cultured embryonic stem cells pluripotent.
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Emerging Evidence for the Pancreatic Progenitor Cell Hypothesis
A contentious debate among diabetes researchers has surrounded the regeneration of pancreatic insulin-producing cells: not if these cells regenerate, but rather how.
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