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"Superplatelets" Could Help Make Trauma More Survivable
A University of British Columbia bioengineer has developed a potential strategy for endowing platelets with extra powers so they can rise to the occasion and continue coagulation.
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‘Bad’ Antibodies Provide Crucial Protection Against Invading Microbes
In a world first, scientists have revealed how a population of 'bad' antibodies in the immune system - which are usually 'silenced' because they can harm the body - can provide crucial protection against invading microbes.
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Lonza Opens World’s Largest Dedicated Cell-and-Gene-Therapy Manufacturing Facility in Texas
First-of-its-kind, state-of-the-art manufacturing facility with capacity to produce treatment for thousands of patients suffering from rare genetic disorders or life-threatening diseases.
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Personalized Tumor Vaccine Shows Promise
A new type of cancer vaccine has yielded promising results in an initial clinical trial. The personalized vaccine is made from patients’ own immune cells, which are exposed in the laboratory to the contents of the patients’ tumor cells, and then injected into the patients to initiate a wider immune response.
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Nasal Vaccine Suppresses Peanut Allergies in Mice
A vaccine may successfully turn off peanut allergy in mice, a new study shows. Just three monthly doses of a nasal vaccine protected the mice from allergic reactions upon exposure to peanut, according to new research.
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IONTAS and IGEM Therapeutics Collaborate to Identify Novel IgE Antibodies
The project will add to IGEM’s pipeline of drugs and expand upon IGEM-F, an IgE targeting ovarian and other cancers, currently in a Phase 1/2a study.
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Drug Combo Improves Survival of Women with Rare Uterine Cancer
Adding the monoclonal antibody drug trastuzumab - already used to treat certain breast cancers - to the chemotherapy regimen of women with a rare form of uterine cancer lengthens the amount of time their tumors are kept from growing, according to Johns Hopkins Medicine researchers conducting a small Phase II trial of the regimen, testing its safety and value.
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Researchers Receive >$2 Million to Eradicate Common Type of Leukemia
Christoph Rader, PhD, associate professor at the Florida campus of The Scripps Research Institute, has been awarded a $2.875 million, five-year grant from the National Cancer Institute to develop unique antibody-drug conjugates engineered to eradicate one of the most common forms of leukemia, chronic lymphocytic leukemia (CLL).
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Small-Molecule Structure Corrector Fixes Genetic Risk Factor for Alzheimer’s Disease
Using human brain cells, scientists at the Gladstone Institutes discovered the cause of—and a potential solution for—the primary genetic risk factor for Alzheimer’s disease, a gene called apoE4.
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Mystery of Malaria Vaccine Target Solved
The human piece of a malaria infection puzzle has been revealed for the first time, solving a long-standing mystery. A protein displayed on the surface of malaria parasites called "TRAP" is a high-priority vaccine target, but how it interacts with human host cells has remained a puzzle.
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