Probiotic “Backpacks” for Treating Inflammatory Bowel Diseases
A new study has shown just how useful some well-equipped gut-friendly bacteria could be for improving treatments of inflammatory bowel disease, including Crohn’s disease and ulcerative colitis.
Cancer Vaccine Improves Tumor-Fighting Action in Animals
An experimental therapeutic cancer vaccine has been shown to alter the tumor microenvironment and boost the number of cancer-fighting immune cells in animal models.
“Mini-Proteins” Block Amyloid Aggregation in Animal Models
Many cell- and neurodegenerative diseases are linked to the formation of toxic protein aggregates. Researchers have developed “mini-proteins” that are able to bind the proteins that form amyloids and prevent their aggregation into cytotoxic amyloids.
Antibodies Preserve Stem Cells Better Than Traditional Drugs in Mouse Brains
According to a study, a stem cell therapy that uses antibodies instead of traditional immunosuppressant drugs robustly preserves cells in mouse brains and has the potential to fast-track trials in humans.
Novel “Branched” Lipid Created for mRNA Delivery
A novel branched, ionizable lipid has been created by researchers to increase the efficiency of mRNA delivery by lipid nanoparticles.
COVID-19 Vaccine “Boosts” Effectiveness of Anti-Cancer Treatment
A collaborative study has found that immunization with the vaccine SinoVac might improve responses to treatment in patients with nasopharyngeal cancer (NPC).
Engineered T Cells Could Help Children With Treatment-Resistant Leukemia
Researchers at UCL and Great Ormond Street Hospital for Children (GOSH) have engineered donor T-cells to try and treat seriously ill children with resistant leukemia, who had otherwise exhausted all available therapies.
Why Vaccine Responses Vary Between Individuals
A meta-analysis has revealed that the level of inflammatory response before vaccination can predict how well an individual responds to a vaccine.
Vaccine Generates Immune Response Against Breast Cancer in Trial
Researchers in a new study describe the development of an experimental vaccine that could be used to prevent or treat an aggressive form of breast cancer, safely generating an immune response against an important driver of breast cancer growth.
Monkeypox Mutations Cause Virus To Replicate and Evade Treatments
The specific mutations to the monkeypox virus that have contributed to the virus becoming more infectious and harder to treat have been identified by a team of researchers.