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Marburg Virus: Workings of the First Promising Treatment Revealed
Scientists have discovered the workings of the first promising treatment for Marburg virus, a pathogen with the same pandemic potential as Ebola virus. The research builds on previous studies showing that an antibody called MR191 can neutralize Marburg—though no one knew exactly how it targeted the virus.
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Targeting Mitochondrial ATP Synthase to Treat Alzheimer's
Alzheimer's drug developed after screening for compounds from plants with an ability to reverse the cellular and molecular signs of aging in the brain.
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Fuel Made From Shale Gas With Innovative Catalyst
New Research shows methane in shale gas can be turned into hydrocarbon fuels using an innovative platinum and copper alloy catalyst. The new alloy catalyst is resistant to coking, so it retains its activity and requires less energy to break the bonds than other materials.
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Engineers Grow Functioning Human Muscle from Skin Cells
First functioning human muscle grown from induced pluripotent stem cells holds promise for cellular therapies, drug discovery and studying rare diseases.
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New Stem Cell Method Sheds Light on a Tell-tale Sign of Heart Disease
While refining ways to grow arterial endothelial cells in the lab, a regenerative biology team at the Morgridge Institute for Research unexpectedly unearthed a powerful new model for studying a hallmark of vascular disease.
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Virus Modified to Deliver Peptide Drugs to Cells
By chipping away at a viral protein, Rice University scientists have discovered a path toward virus-like, nanoscale devices that may be able to deliver drugs to cells.
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Analyzing Cellular Receptors Using AI to Determine Immunotherapy and Vaccine Response
Johns Hopkins scientists have used a form of artificial intelligence to create a map that compares types of cellular receptors, the chemical "antennas" on the surface of immune system T-cells. Their experiments with lab-grown mouse and human T-cells suggest that people with cancer who have a greater variety of such receptors may respond better to immunotherapy drugs and vaccines.
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Common Prescription Drug May Boost Melanoma Immunotherapy
Patients who receive immunotherapy while taking a specific type of beta blocker live longer than patients who receive immunotherapy alone.
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£70M Meant for Cancer Drug Development is Reassigned to Prepare for Brexit
At the end of last year, the Health Committee held a meeting to discuss Brexit, more specifically the impact this will have on the discovery, development and regulation of medicines, medical devices and biopharmaceuticals.
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Repeated Influenza Vaccination Effectively Prevents Severe Flu in Older Adults
Repeated vaccination for influenza in older adults reduced the severity of the virus and reduced hospital admissions, found new research published in CMAJ.
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