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An research team have been developing a personalized mRNA cancer-treatment vaccine approach. It is designed to help immune cells recognize specific neoantigens on patients’ pancreatic cancer cells.

Mount Sinai researchers have published what they say is the first study to identify a new form of treatment for rapid eye movement (REM) sleep behavior disorder.

Data from a Mount Sinai-led phase 3 trial published today in The New England Journal of Medicine show that upadacitinib, a breakthrough, once-daily oral medication, helps patients achieve and maintain clinical and endoscopic remission.

Word choice matters—a lot— when it comes to research. That's the conclusion of a new study that analyzed HIV-related stigmatizing language published in scientific literature from 2010 to 2020.

A new tool which could help reduce the spread of antimicrobial resistance is showing early promise, through exploiting a bacterial immune system as a gene editing tool.

Hematopoietic stem cells can be transplanted into patients to treat various blood disorders, but this usage is limited by barriers to cell growth and expansion in the lab. A new system from the University of Tsukuba may have the answer.

A trial of a new vaccine against meningococcal disease, a cause of meningitis and blood poisoning, has found that it is safe and induces a strong immune response across five strains of meningococcal bacteria: A, C, W, Y and X.

By comparing the structures of protein complexes from different lineages of the dangerous Lassa virus, a Scripps Research team identified new antibodies and vaccine targets.

Researchers have engineered bacteria to produce an unnatural amino acid with a rare functional group that has implications in immune system regulation, providing a foundation for developing future immunotherapies.

Vaccines against smallpox given until the mid-1970s offer continuing cross-reactive immunity to mpox (previously known as monkeypox), researchers from Karolinska Institutet in Sweden report.