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CRISPR-Cas Could Reduce the Spread of Antimicrobial Resistance
A new tool which could help reduce the spread of antimicrobial resistance is showing early promise, through exploiting a bacterial immune system as a gene editing tool.
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Novel Culture System Improves Growth of Blood Stem Cells in the Lab
Hematopoietic stem cells can be transplanted into patients to treat various blood disorders, but this usage is limited by barriers to cell growth and expansion in the lab. A new system from the University of Tsukuba may have the answer.
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Vaccine Trial Results Boost Hope of Eliminating Meningitis by 2030
A trial of a new vaccine against meningococcal disease, a cause of meningitis and blood poisoning, has found that it is safe and induces a strong immune response across five strains of meningococcal bacteria: A, C, W, Y and X.
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The Critical Protein Complex That Helps Lassa Virus Infect Human Cells
By comparing the structures of protein complexes from different lineages of the dangerous Lassa virus, a Scripps Research team identified new antibodies and vaccine targets.
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Bacteria Created That Can Synthesize an Unnatural Amino Acid
Researchers have engineered bacteria to produce an unnatural amino acid with a rare functional group that has implications in immune system regulation, providing a foundation for developing future immunotherapies.
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Smallpox Vaccines Given Until the Mid-1970s Offer Mpox Immunity
Vaccines against smallpox given until the mid-1970s offer continuing cross-reactive immunity to mpox (previously known as monkeypox), researchers from Karolinska Institutet in Sweden report.
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Fast-Aging Mice Live Longer When Oxygen Is Restricted
Massachusetts General Hospital scientists have, for the first time, shown that oxygen restriction increases lifespan in a mouse model of aging. The research is published in PLOS Biology.
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“Lost” Immune Cells Contribute to Reduced Vaccine Response in Elderly
Understanding the ways our immune response changes as we age holds the key to designing better vaccines and boosting protection for people most at risk.
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Scientists Call for Tighter Regulation of Stem Cell Treatments
After finding hundreds of clinics worldwide offering unproven stem cell "therapies" for conditions including Parkinson's and hair loss, scientists are calling for tighter regulation of stem cell treatments.
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Risk Biomarkers Could Predict Serious Side Effect of Stem Cell Transplant
Doctors are one step closer to having a risk biomarker to alert them to which of their pediatric stem cell transplant patients are likely to experience a potentially deadly side effect called sinusoidal obstruction syndrome.
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