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Gene Therapy for Dogs Ready for Human Clinical Development
A successful gene therapy trialed at Michigan State University in dogs with an inherited eye disease is ready to be developed for clinical use in human patients with a rare condition called retinitis pigmentosa.
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Human Viruses Thwarted by "Gene Scissors"
The replication of potentially harmful adenoviruses can be significantly reduced in human cells in cell culture by using the CRISPR-Cas9 system or "gene scissors," a study has shown.
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Promising Results in Trial of First “Gene-Silencing” Drug for Alzheimer’s Disease
A world-first trial has found a new genetic therapy for Alzheimer’s disease that is able to safely and successfully lower levels of the harmful tau protein known to cause the disease.
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A “Mini Gene” Therapy for Rare Disease That Causes Blindness and Deafness
Researchers have used a "mini gene" therapy to replace a mutated gene in Usher Syndrome – which causes blindness and deafness.
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Ingestible “Electroceutical” Capsule Boosts Appetite Hormone Levels
A new study in animal models has shown how an electrical capsule can stimulate stomach cells to produce the appetite-stimulating hormone ghrelin, which may one day help to treat conditions involving nausea or appetite loss.
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Gene Therapy Improvements Made Through Adeno-Associated Virus Vector Bioengineering
A new study characterizes a bioengineered adeno-associated virus (AAV)3B capsid variant that demonstrates improved transduction to human liver cells.
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Mobile Vaccine Printer Could Help Vaccines Reach More People
A mobile vaccine printer, developed by MIT researchers, could be used to scale up vaccine production and help vaccines reach more people.
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Cranberry Products Can Prevent UTIs, Large-Scale Review Suggests
Old Wives’ tales are often considered to be nothing more than folklore, but a new review study suggests there is scientific evidence supporting the use of cranberry products for urinary tract infections (UTIs). The data is published in The Cochrane Database of Systematic Reviews.
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Vulnerable Groups Were Least Likely To Have COVID Vaccination
A large-scale registry study in Finland has identified several factors associated with uptake of the first dose of COVID-19 vaccination. In particular, persons with low or no labor income and persons with mental health or substance abuse issues were less likely to vaccinate.
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Cell “Backpack” Therapy Reduces MS Disease Burden in Model
Myeloid cells armed with "backpacks" of anti-inflammatory molecules have been used to treat symptoms of multiple sclerosis (MS) in mouse models.
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