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New Procedure To Find and Quantify Unintended Errors in Genome Editing
A Rice University lab is leading the effort to reveal potential threats to the efficacy and safety of therapies based on CRISPR-Cas9, the Nobel Prize-winning gene editing technique, even when it appears to be working as planned.
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Intranasal COVID-19 Vaccine Protects Against Variants in Animals
Researchers have developed an intranasal vaccine for COVID-19 that, in hamsters, can fight off the original virus and two variants.
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Oxytocin Derivative Improves Cognitive Impairment in Mice
An oxytocin derivative has been designed to be delivered intranasally, and studies in mice have shown that it can reverse amyloid beta-induced cognitive impairment.
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Transcription Factor Required for Preprograming of Heart Fibroblasts Discovered
One promising strategy to remuscularize the injured heart is the direct cardiac reprogramming of heart fibroblast cells into cardiomyocytes. Researchers have identified TBX20 as the key missing transcription factor in existing cocktails for direct cardiac reprogramming of human fibroblasts.
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Genetic Study of Polynesian Population Offers Insights on High Cholesterol
Researchers have found a genetic variant that is relatively common among people of Polynesian ancestry but rare in most other populations and could improve understanding of the genetic underpinnings of high cholesterol in all people.
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Hope That Panama Disease in Bananas Can Be Controlled
According to research, major classes of fungicides do not work against a new race of the fungus that causes Panama disease in banana plants, but a more specialized class of anti-fungal chemistries could suppress disease and maintain banana plant health.
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Hepatitis B Vaccine Regimen Protects People With HIV in Clinical Trial
Results from an ongoing clinical trial show that a three-dose course of a hepatitis B vaccine protects people with HIV from contracting hepatitis B.
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Myocarditis Risk Seven Times Higher With COVID-19 Infection Than Vaccines
The risk of developing inflammation of the heart muscle is seven times higher with COVID-19 infection compared to the COVID-19 vaccine, according to a new study.
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New Drug Opportunities From Mushrooms That Grow on Insects
A mushroom that infects and kills insects has been known to produce a bioactive compound that could be used as an antiviral or cancer drug, but growing these fungi in the lab has proved to be challenging, until now.
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New Gene Target for Treatment-Resistant Brain Cancer
Researchers have identified a gene that may provide a therapeutic target for the deadly, treatment-resistant brain cancer glioblastoma multiforme.
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