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Researchers Link ‘Epigenetic’ Changes to Inflammation-Induced Colon Cancer
Johns Hopkins Kimmel Cancer Center scientists report that sharp rises in levels of reactive oxygen molecules, and the inflammation that results, trigger biochemical changes that silence genes in a pattern often seen in cancer cells. The researchers confirmed this gene-silencing effect in mice that develop inflammation-induced colon cancer.
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Using Epigenetics in Lung Cancer
In a paper published in Cancer Discovery, researchers have used epigenetic therapy to target non-small cell lung cancer (NSCLC) by switching silenced genes back on.
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Epigenetic MGMT Test Enters Phase III Brain Cancer Study
MDxHealth announced it has entered into a companion diagnostic agreement with Prof. Dr. Ulrich Herrlinger of the Division of Clinical Neuro-oncology of the University Hospital of Bonn (Germany) to provide MGMT epigenetic testing.
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TRACON Pharmaceuticals Announces Appointment of Kenneth Galbraith as Chairman of the Board
The privately held biopharmaceutical company, which focuses on the development of cancer therapeutics, announced the appointment of Kenneth Galbraith as Chairman of the Board.
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Anthera Pharmaceuticals Appoints Chief Technology Officer
Anthera Pharmaceuticals announces that Dr Debra Odink has been promoted to the role of Chief Technology Officer and Senior Vice President.
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Pfizer Maneuvers to Protect Lipitor from Generics
Lipitor is so valuable that Pfizer is practically paying people to keep taking its blockbuster cholesterol medicine after generic competition hit the U.S. market last week.
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Philippine Gov't Boosts Genome-Based Research
The Department of Science and Technology (DoST) assured full commitment to the advancement of genome-based research in the country to boost and revolutionize health, drug discovery, forensics, agriculture and related researches.
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Gene Rearrangements Linked to Breast Cancer
Alterations behind seven percent of all breast cancers Identified. Two other rearrangements associated with prostate and lung cancer could also be behind five to seven percent of all breast cancers, according to US scientists.
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More Evidence Links Specific Genes to ADHD
Variations in genes involved in brain signaling pathways appear to be linked to attention-deficit/hyperactivity disorder (ADHD), according to a new study. Researchers believe future treatments might target these genetic pathways.
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Inviragen Initiates a Phase 2 Clinical Study of DENVax
Positive phase 1 safety and immunogenicity results to be presented at 2011 ASTMH meeting.
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