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Rare Blood Clots Linked to COVID-19 Vaccines: What’s the Molecular Mechanism?
An international team of scientists believe they may have found a molecular mechanism behind the extremely rare blood clots linked to adenovirus COVID-19 vaccines.
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First Head-to-Head Comparison of Pfizer and Moderna Vaccines
In the first head-to-head comparison of the effectiveness of the Pfizer-BioNTech and Moderna COVID-19 vaccines, researchers have found that the Moderna vaccine offered an increased level of protection.
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RNA “Gatekeeper” in Gene Expression Opens Door for New Drug Targets
According to a new study, an important player in the healthy development of female embryos turns out also to play a key role in regulating the behavior of chromosome loops and gene expression in both sexes.
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How To Freeze-Dry a Potential COVID-19 Vaccine
Things that are freeze-dried: Astronaut food. Emergency rations. And, just maybe, some future COVID-19 vaccines.
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Rattlesnake Venom Protein Aids Development of Blood Clotting Drug
Researchers have developed a molecule of pharmaceutical interest from a protein found in rattlesnake venom. The molecule, now called PEG-rCollinein-1, is a possible drug candidate to modulate blood clotting.
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New Strategy for Antibodies To Disable Viruses
Researchers found that the same type of antibody can neutralize Zika and dengue viruses in two different ways — one where it binds to the virus and deactivates it, which is the traditional way we think about antibody activity, and the other where it burrows in and distorts the virus.
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New Method To Precisely Correct Genetic Alterations in Cultured Patient Cells
The method produces genetically corrected autologous pluripotent stem cells from a 2-3 mm skin biopsy from patients with different genetic diseases. The corrected stem cells are essential in the research and for the development of new therapies for the diseases in question.
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Exploring the Potential of Cancer-Crushing Viruses
It’s hard to imagine viruses as something other than hostile enemies to be vanquished, but in a recent review article, researchers describe a class of viruses that act to combat rather than cause deadly disease.
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Packaging mRNA Inside Flu Virus Shells for Efficient Delivery
Nanoengineers at the University of California San Diego have developed a new and potentially more effective way to deliver messenger RNA (mRNA) into cells. Their approach involves packing mRNA inside nanoparticles that mimic the flu virus—a naturally efficient vehicle for delivering genetic material such as RNA inside cells.
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$4M Grant Will Help To Advance New CAR T-Cell Therapy
A $4.1 million grant has been approved to enable researchers to advance a new chimeric antigen receptor (CAR) T-cell therapy from the laboratory into the clinic.
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