CAP-CMV GmbH Raises New Funds to Further Develop its Novel hCMV Vaccine
News Mar 25, 2014
CAP-CMV GmbH has announced that it has raised in total € 1.7 m from its investors Peppermint Venture Partners (PVP), NRW.Bank, Creathor Venture, KfW and private investors in a combined seed/start-up investment.
The funds will be used to advance further it´s vaccine candidate, HCMV dense bodies (DBs) derived from CEVEC´s human CAP cell technology.
DBs contain highest amount of relevant antigens, and were shown to elicit strong and lasting humoral and cellular immune responses in preclinical models.
DBs are the ideal vaccine candidate to prevent hCMV caused diseases. Congenital infection with hCMV is a leading cause for neonatal disabilities. As up to 40% of the population carry this virus the hCMV infection is also a major health threat to recipients of solid organ or stem transplantations.
Wolfgang Kintzel, start-up CEO of CAP-CMV comments: “We are very happy that we could now secure our Series A financing round for this unique vaccine project. The money will be used to prove in various animal studies the clear advantages of our system against other technologies as well as advancing our pre-clinical programs.”
Also in March CAP-CMV´s shareholders appointed Albrecht Läufer as its new CEO. Joachim Rautter, Managing Partner at PVP, and speaker of CAP-CMV´s advisory board says: “Wolfgang has put CAP-CMV on the right track and we thank him for his tremendous efforts to establish the company. We now welcome Albrecht and wish him success in taking forward CAP-CMV on its growth path while Wolfgang will be appointed to the board of CAP-CMV”.
Albrecht Läufer was cofounder and first CEO of Vakzine Projekt Management GmbH (VPM), the company which has started preclinical development of HCMV dense bodies and then licensed the project to CAP-CMV.
Small Tweak Makes Progress Towards Improved Flu TreatmentNews
Researchers report that a tweak to a small-molecule drug shows promise for future production of new antiviral therapies that could help patients, regardless of the strain with which they are infected.READ MORE
H7N9 Influenza Vaccine Clinical Trials CommenceNews
Two new clinical trials testing an experimental vaccine to prevent influenza caused by an H7N9 influenza virus are now enrolling volunteers at sites across the United States. The Phase 2 studies will test different dosages of the inactivated influenza vaccine candidate as well as different vaccination schedules. The studies also will evaluate whether an adjuvant boosts the immune responses of people receiving the vaccine.
Antigen Study Shows Promise for a Respiratory Syncytial Virus VaccineNews
Medical researchers have been trying to develop a vaccine for respiratory syncytial virus (RSV) for more than 50 years, without success. New findings however, point to a promising route for designing an effective vaccine. Researchers determined the atomic structure of RSV G (major viral surface protein) and identified two sites on it that are targeted by protective antibodies effective against a broad range of RSV strains.READ MORE