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CAR T Cell Therapy Shows Promise in Acute Myeloid Leukemia

News   May 10, 2018 | Original story from Moffitt Cancer Centre

 
CAR T Cell Therapy Shows Promise in Acute Myeloid Leukemia

Relapsed AML patient treated with CYAD-01 CAR-T therapy. CD34 IHC of the core biopsy shows clusters of blasts (~7%) consistent with relapsed disease (Panel A). Prominent dysmegakaryopoiesis was also noted (Panel B). BM biopsy at day +56 following 3 infusions of CYAD-01 showed normal trilineage hematopoiesis with CD34 IHC showing no increase in blasts (Panel C). Patient also with significant improvement of hematopoiesis as transfusion independent with marked increase of hemoglobin and platelet count (Panel D). Credit: doi:10.3324/haematol.2017.186742

 
 
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