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Malaria Antibodies Show Team-work: Remarkable Images Captured

News   Oct 24, 2018 | Original story from Scripps Research

 
Fascinating Antibody Interactions Provide Insights for Malaria Vaccine Design

The cryo–electron microscopy structure of a highly protective monoclonal antibody reveals an extended spiral conformation of the central NANP repeat region surrounded by antibodies. This unusual structure appears to be stabilized and/or induced by interaction with an antibody where contacts between adjacent Fabs are somatically mutated and enhance the interaction. Oyen et al. 2018. Image credit: Scripps Research

 
 
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