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Novel Approach for Cooling and Storing Vaccines

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Oak Ridge National Laboratory researchers have retrofitted a commercial refrigeration container designed to ensure COVID-19 vaccines remain at ultra-low temperatures during long transport and while locally stored.


Most COVID vaccines, depending on the manufacturer, are stored at minus 70 or 30 degrees Celsius. Current transport methods use dry ice to maintain desired temperatures. However, longer travel times, particularly to remote locations without supportive infrastructure, require extended refrigeration.


In a study, researchers collaborated with Carrier and created a testbed using a lightweight aluminum container equipped with a refrigeration system, vaccine packages and optimal cargo layout and storage rack design that kept temperatures consistent and uniform throughout the container. Simulation studies demonstrated this method can hold required temperatures twice as long.


“We significantly increased the dry ice life, providing reliable temperature control and a safe, secure solution for cooling vaccines for transport and last mile storage,” ORNL’s Jian Sun said.


Reference: Sun J, Zhang M, Gehl A, et al. COVID 19 vaccine distribution solution to the last mile challenge: Experimental and simulation studies of ultra-low temperature refrigeration system. Int J Refrig. 2022;133:313-325. doi: 10.1016/j.ijrefrig.2021.11.005


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