A Rapid and Effective Tool for Monitoring Monoclonal Antibody Production
Poster Aug 13, 2014
B. Bhullar, Ph.D., Carlina Hui, B.Sc., M. Hariharan, M.Sc., J. Hewitt, B.Sc , and N. Vats, Ph.D.
IVD manufacturers must establish QC systems to assure that the product received is suitable for use. As an alternative to laborious time consuming conventional methods such as ELISA or dot immunobinding, we examined the effectiveness and utility of rapid point-of-use immuoanalytical tools created with MedMira's MiriadTM RVF Toolkit to quickly assess the suitability of hybridoma bioreactor supernatants.
Quantitative Cell-Based Bioassays for Individual and Combination Immune Checkpoint Immunotherapy TargetsPoster
The human immune system is comprised of a complex network of immune checkpoint receptors that are promising new immunotherapy targets for the treatment of a variety of diseases including cancer and autoimmune-mediated disorders.READ MORE
Applications of chemically modified synthetic guide RNA for CRISPR-Cas9 genome editingPoster
Our results indicate that MS modifications are required for experiments with co-electroporation of Cas9 mRNA and synthetic gRNA, yet have no impact on editing efficiency when delivered with lipid-based transfection reagents.READ MORE
Highly Accurate HCV Genotyping by Targeted Next Generation SequencingPoster
The recent fast advancement of next generation sequencing (NGS) technologies allowing for unprecedented speed and accuracy in analyzing viral genomes are opening new ways to further improve diagnostic genotyping of HCV.