Acute Infective Endocarditis: Early Surgery versus Conventional Treatment
Poster Aug 06, 2012
Yassar Abdullah S Alamri
Athough first described in the mid-16th century, IE remains considerable cause of cardiovascular morbidity and mortality to date. Early surgery for IE (defined as valvular surgery within 1 to 7 days of hospital admission) has lately been theorised to confer superior outcomes compared to the current standard of care (i.e. antibiotics with or without delayed surgery).
Touching BACE. How Inhibiting β-Amyloid Production by Steric Hindrance with a Novel Immunotherapy Improves Memory in PDAPP MicePoster
The work presented in this poster aims to assess whether intracerebroventricular (ICV) administration of 2B3 alleviated age dependent memory deficits in PDAPP mice and to determine whether 2B3 altered APP metabolism and NMDA receptor phosphorylation ex vivo.READ MORE
Multiplexed Cell- and Bead-based Assays in a No-wash Format for Biologics Screening and CharacterizationPoster
Here we present the results generated from multiplexed no-wash protocols using TTP Labtech’s mirrorball, a laser scanning cytometer.READ MORE
Quantitative Cell-Based Bioassays for Individual and Combination Immune Checkpoint Immunotherapy TargetsPoster
Immune checkpoint receptors are promising new immunotherapy
targets for the treatment of a variety of diseases including cancer and
autoimmune-mediated disorders. We developed a suite of cell-based
bioluminescent reporter bioassays for individual and combination
immune checkpoint immunotherapy targets including: PD-1 (PD-L1 or PD-L2), CTLA-4, LAG-3, TIGIT, PD-1+TIGIT, GITR, 4-1BB, CD40, and OX40.