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An IgG Cleaving Protease from S equi with Improved Activity Against Mouse IgGs

Poster

Published: October 9, 2015

An IgG Cleaving Protease from S equi with Improved Activity Against Mouse IgGs content piece image

Here we have expressed and purified a modified recombinant IdeZ, and show that it has significantly improved activity against mouse IgG2a and IgG3 subclasses when compared to IdeS. We also demonstrate the use of IdeZ in LC-MS workflows for human and mouse IgG characterization.