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Heparan Sulfate Antibodies Accelerate Glycobiology Research

3G10 antibody staining (green) for Heparan Sulfate on HUES7 cells following Heparinase III digestion.
Credit: the Merry Lab, University of Nottingham UK.
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Working with leading research institutions, Amsbio has established itself as a premier supplier of high quality Heparan Sulfate (HS) monoclonal antibodies driving breakthroughs in Glycobiology research.


Heparan Sulfate (HS) is widely distributed on cell surfaces and basement membranes in mammals. It participates in important biological processes due to displaying specific interactions with many biologically active proteins. However, due to its non-immunogenic nature, developing effective antibodies against HS has long been a challenge.


Amsbio has overcome these limitations by offering a range of hybridoma-derived anti-HS antibodies such as 10E4, 3G10, and JM403 that are valuable tools for research. The popularity of our Heparan Sulfate antibodies is because of their high sensitivity, specificity, and affinity to target antigens plus they work across many model species. All Heparan Sulfate antibodies supplied by Amsbio are rigorously validated to accurately detect and quantify cell surface Heparan Sulfate, ensuring reliable data for diverse applications from investigating viral infections to exploring cancer and immunological disorders. When preserved using CELLBANKER® cryopreservation media, cell surface HS integrity is maintained, ensuring reliable and reproducible results in downstream assays.


To provide an informed backgrounder on the importance of glycobiology, Amsbio has cooperated with Dr Doug Dyer, an immunology researcher at the University of Manchester, UK, to create an original blog - https://www.amsbio.com/news/sweet_science. In this blog, Dr Dyer discusses and illustrates with research citations, how glycobiology is increasingly being recognized as the “dark matter” of biology, with new research revealing that incorporating glycans into our understanding is redefining fundamental biological processes. At the forefront of these advances, Amsbio has established itself as a premier supplier of high-quality tools, including their flagship Heparan Sulfate monoclonal antibodies.