Vectron Biosolutions Obtains Strong Results for Biosimilar Production
Product News Feb 15, 2012
Vectron Biosolutions has announced that they have obtained strong results for manufacture of selected biosimilar proteins using their proprietary E. coli expression technology.
The study was done side-by-side with other expression technologies and Vectron’s technology gave higher soluble and/or insoluble yields for seven out of 10 tested biosimilar proteins.
The increase in yield was 2 to 25 times compared to the best conventional technology.
The biosimilar proteins that were produced more efficiently with Vectron’s technology than with other technologies were human growth hormone, interferon β-1b, TNF α-1a, IGF-1, insulin, IL-2, and IL-1RA.
“Demonstrating that our technology is superior for manufacture of many valuable therapeutic proteins is a major milestone for us,” commented CEO in Vectron Biosolutions AS, Trond Erik Vee Aune.
Vee Aune continued, “Significant increases in soluble and insoluble yields translate directly to large savings in cost of goods for our pharmaceutical partners, especially in the highly competitive biosimilars market where cost-efficient manufacturing processes are essential. In addition, demonstrating that our technology can be used to obtain many-fold higher titers means that our services and technology is highly suitable for new therapeutic proteins being developed, especially those where low solubility and/or low yields are a complicating issue.”