ioMicroglia™ – consistent iPSC-derived microglia, ready in 10 days! content piece image

Product

ioMicroglia™ – Consistent iPSC-Derived Microglia, Ready in 10 Days!

Name: ioMicroglia™ – Consistent iPSC-Derived Microglia, Ready in 10 Days!
Brand: bit.bio

ioMicroglia are cryopreserved human iPSC-derived microglia powered by bit.bio’s opti-ox™ precision reprogramming technology, built so scientists no longer have to battle with long differentiation protocols that produce inconsistent cell populations.

In just 10 days post-revival, ioMicroglia show:

A typical ramified morphology

Consistent and defined cell populations

Expression of key phenotypic markers (TMEM119, P2RY12, IBA1, TREM2, CX3CR1, CD11b, CD45, and CD14)

A transcriptomic signature with high equivalence to primary adult and foetal microglia

Key human microglia functions with lot-to-lot consistency, including mediating an inflammatory response, disposal of unwanted materials, and carrying out immune surveillance.

Co-culture compatibility with bit.bio ioGlutamatergic Neurons, to gain insights into complex intercellular interactions.

ioMicroglia are available now. Request a quote today.

Product Specifications

Marker expression TMEM119, P2RY12, IBA1

Vial size 1.5 million viable cells

Shipping format Cryopreserved

Viability >80%

Seeding density 37,000-39,500 cells/cm²

Seeding compatibility 6, 12, 24, 96 and 384 well plates

Validated functions Phagocytosis, cytokine secretion, co-cultures with neurons

Price Available on request

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