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NEW Thermo Scientific™ Vanquish™ Core HPLC systems

NEW Thermo Scientific™ Vanquish™ Core HPLC systems


The NEW Thermo Scientific™ Vanquish™ Core HPLC systems provide exceptional analytical precision, detector sensitivity, and operational simplicity to enable unprecedented reliability and robustness. Designed specifically for routine analysis laboratories the Vanquish Core HPLC systems provide:


  • Dependable system uptime through innovative system health checks and improved system ruggedness
  • Simple integration into existing infrastructure by enabling control under Thermo Scientific™ Chromeleon™ Chromatography Data System (CDS) software
  • Compliant-ready infrastructure that minimizes unexpected results and out-of-specification events
  • Empower lab personnel with intuitive system operation and simplified user maintenance
  • Seamless method transfer from all common HPLC systems
  • Smooth integration into the broad Thermo Scientific LC-MS portfolio
Simple to the Core

Features of the Vanquish Core include:

Vanquish Solvent Monitor
Use the Vanquish Solvent Monitor to increase your regulatory compliance, productivity, and safety of your laboratory. That device guarantees that your HPLC systems will never run dry and the waste will not spill over, reducing loss of valuable measurement time and sample material.

Vanquish User Interface
With the Vanquish User Interface, you are the master of your LC instrument. The display always shows you the key parameters of your instrument such as flow and pressure and guides you in a visual step-by-step video tutorial through key maintenance tasks.

Detection capabilities
Differing molecular characteristics of your analyte, from small molecules to complex biomolecules, necessitates multiple detector technologies. The Vanquish Core systems have been built to utilize a wide range of analytical detectors, including mass spectrometry (MS), diode array detection (DAD), multi wavelength detection (MWD), charged aerosol detection (CAD), variable wavelength detection (VWD), and fluorescence detection (FLD).

SmartInject Technology
Superior retention time precision and accuracy, as well as enhanced column protection.

Proprietary injection and switching valves
The valves used in the Vanquish Core HPLC systems are designed to meet the reliability needs to make HPLC run robustly and routinely. The valves are long-life and follow a no maintenance philosophy reducing your overall cost of ownership.

Easier operation
Utilizes tool-free Thermo Scientific ™ Viper™ Fingertight Fittings with near-zero dead volume operation and ergonomic design.

Simple maintenance
Modules can be repaired without de-stacking; each unit has handles for ease of maneuvers; light bars on the front of the system indicate system status; and the entire system supports tool-free maintenance.

Keep your lab tidy
The built-in drawer stores accessories, related documents, or any other useful material for the system.

Easy to adopt
The tunable gradient delay volume and multiple thermostatting options allow you to precisely replicate your legacy HPLC methods.

Compatible with your software infrastructure
Support under various software environments, including the latest Chromeleon CDS feature release and long-term support versions.