Advanced Cell Models – Multimedia

This Teach Me in 10 will explain how the human brain vasculature can be modeled using new, microfluidic organ-on-a-chip technology.

This Teach Me in 10 will cover best practices to consider for organoid work, as well as how to use Corning Matrigel matrix and other products to support organoid models in research.

Speaking at the online symposium, Innovations in Disease Modeling 2022, Dr. Mehmet R. Dokmeci, Associate Professor at the Terasaki Institute for Biomedical Innovation presented his talk on microscale sensors and systems for tissue engineering.

In this episode, Lucy Lawrence and Michiel Fokkelman will discuss the concept of high content imaging of 3D-cultured organoids in combination with high throughput screening as a service for drug discovery and pre-clinical drug development.

Speaking at the online symposium, Innovations in Disease Modeling 2022, Dr. Donald E. Ingber, Founding Director of Wyss Institute for Biologically Inspired Engineering at Harvard University, presented his talk on novel human organ-on-a-chip technologies

Dr. Joseph Regan speaks to Lucy Lawrence and shares information from a recently published protocol for the isolation and functional validation of label-retaining quiescent colorectal cancer stem cells from patient-derived organoids for RNA-seq.

Speaking at Innovations in Disease Modeling, Sasha Mendjan, Group Leader at Institute of Molecular Biotechnology, presented his talk on aims to recapitulate human heart development in vitro, discover the molecular mechanisms driving cardiac self-organization, and how this fails in congenital heart disease..

Download this listicle to explore how organ-on-a-chip systems are being used to research rejected therapeutics for autoimmune disorders, model diseases, screen drugs and assay toxicity, and discover antiviral therapeutics and prophylactics.

Current in vitro models of the small intestine offer limited predictivity due to their reliance on immortalized cell lines and static culture. To better predict human response to drug candidates, researchers need a model than can more closely recreate the intestinal microenvironment.

To successfully use these models across a variety of research disciplines and applications, approaches that reduce variability and technology pipelines to image and quantify these complex cell models are required.