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Biomarkers – Multimedia

Video

Oncology Biomarker Testing Current US Practice Baseline and Emerging Trends

This presentation will outline key issues in oncology biomarker testing and describe findings from a study of practices used by National Cancer Institute (NCI) designated cancer centers, the leading U.S. oncology institutions, for testing key biomarkers in three solid tumors - breast, gastroesophageal and non-small cell lung cancers.
Video

Imaging Biomarkers - Future or Reality

Imaging has been at the heart of Medicine for many decades. However, its influence is changing as the need increases not only for diagnosis of disease, but also for quantification of disease extent, identification of suitable candidates for treatment and for testing of both treatment response or assessment of potential side effects for new treatments.
Video

Fit-for-Purpose Biomarker Assay Validation - From Research Tool to Diagnostic Test

Jeff Cummings presents a worked example of circulating tumour cell enumeration as a prognostic/predictive biomarker in cancer research.
Video

New Metabolomics Biomarker for Heart Failure

Metabolomics has been successfully applied to identify and validate biomarkers for congestive heart failure. Diagnosis and risk stratification of heart failure (HF) is challenging.
Video

Creating a Clinical Diagnostic Test from Discovery Through Launch with Mass Spectrometry

Targeted mass spectrometry, called MRM or SRM, allows for the rapid quantification of hundreds of proteins in a single assay. This tool is very specific, highly quantitative and requires very little sample (e.g. < 5 uL plasma).
Video

Biomarkers to Predict Aggressive Prostate Cancer

Claire Morgan discusses the need to identify a panel of biomarkers that may distinguish indolent cancer from aggressive metastatic disease when used collectively.
Alterations in serum thrombotic biomarker in patients with acute myocardial infarction  content piece image
Poster

Alterations in serum thrombotic biomarker in patients with acute myocardial infarction

A combination of these biomarkers could serve as a useful biomarker tool to assess the prognosis of AMI. (This study was supported by National Plan for Science and Technology Program by King Saud University Project Number 08-BIO571-02).
Non-invasive Liquid Biopsy content piece image
Poster

Non-invasive Liquid Biopsy

Paramagnetic Dynabeads® magnetic beads provide a versatile, automation friendly tool for fast sensitive and high throughput isolation that can be tailored to isolate specific circulating biomarkers such as cells, exosomes and nucleic acids.
Video

Biomarkers from Discovery to Clinical Diagnostics Applications of Single-Molecule Array (Simoa) Technology

Andreas Jeromin, Atlantic Biomarkers, speaking at Diagnostics & Biomarkers 2015.
Electric Field-Induced Release and Measurement (EFIRM) can detect EGFR mutations directly from body fluids of lung cancer patients content piece image
Poster

Electric Field-Induced Release and Measurement (EFIRM) can detect EGFR mutations directly from body fluids of lung cancer patients

In patients with NSCLC, Electric Field–Induced Release and Measurement (EFIRM) can detect EGFR mutations directly in saliva. This enables clinicians to adjust their therapeutic strategies in a timely fashion, consequently improving the clinical outcome of EGFR-targeted therapy.
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