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Biomarkers – News and Features

Neurons in the brain with a buildup of Alzheimer's-related tau protein plaques.
News

Alzheimer’s Vaccine Shows Promise in Animal Studies

An experimental vaccine that blocks Alzheimer's-related tau protein buildup has generated a robust immune response in both mice and non-human primates, building on earlier research.
A scientist holding a 96-well plate on a lab bench, commonly used in phenotypic screening of drug compounds.
Article

Phenotypic Screening: A Powerful Tool for Drug Discovery

Phenotypic screening has re-emerged as a powerful strategy for identifying drugs based on their observable effects. Discover how phenotypic screening accelerates drug discovery, supports drug repurposing and enables novel therapeutic breakthroughs.
Star-shaped neurons form dendrites, reaching out to one another.
News

Microglia Engineered Into Living Couriers for Alzheimer's Drugs

Microglia can be engineered to detect disease-specific brain changes – like amyloid plaques in Alzheimer’s disease – and deliver therapeutics exactly where needed.
Cancer cells (red) infiltrating healthy cellular environment (blue).
News

Tumor By-Product Found To Suppress Immune Response

A team of researchers from the University of Chicago, has identified a novel oncometabolite that accumulates in tumors and impairs immune cells’ ability to fight cancer.
Researcher inspecting a blood sample tube, with multiple more samples in a sample rack.
News

Researchers Develop RNA Blood Test To Detect Cancers

Stanford Medicine researchers have created a liquid biopsy test capable of detecting cancers, molecular mechanisms of resistance to treatment and tissue injury.
Two older Black women with menopause doing exercise in a park.
News

Hormone Therapy May Improve Heart Health in Menopausal Women

A study focused on menopausal women found that estrogen-based hormone therapy improved biomarkers associated with cardiovascular health over time. In particular, the study suggests that hormone therapy may lower levels of lipoprotein.
Doctor pointing at brain scan images on a screen, analyzing for signs of Alzheimer's disease.
News

Age, Sex and Genetics Affect Blood Biomarkers for Dementia

A long-term study reveals how age, sex, genetics, and menopause influence blood biomarkers related to dementia. The study tracked neurofilament light chain proteins, glial fibrillary acidic proteins, and phosphorylated tau 181.
A DNA helix, illustrating genetic analysis.
News

A New Way To Track and Predict Aging

Research has uncovered a new way to measure changes in DNA that predict a person's age.
A doctor examines multiple brain scans on a screen using a pen to point at the images, possibly related to Alzheimer's disease.
News

Alzheimer’s Disease Could Be Detected 11 Years Early With New Blood Biomarker

A study identifies beta-synuclein in blood as a potential early biomarker for Alzheimer’s disease. This protein’s levels rise 11 years before cognitive symptoms, offering promise for early diagnosis and improved treatment outcomes.
Scientist wearing blue gloves placing blood sample into sample rack.
News

Gene-Based Blood Test for Melanoma Could Spot Early Indicators of Cancer’s Return

Researchers showed that approximately 80 percent of stage 3 melanoma patients who had detectable levels of circulating tumor DNA (ctDNA) before they started treatment to suppress their tumors went on to experience recurrence.
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