Biomarkers – News and Features

Researchers from BC Cancer Research Institute and University of British Columbia studied 40 night shift workers in a randomized, placebo-controlled trial. A 3 mg melatonin dose taken before daytime sleep raised DNA repair markers by 80%.

The use of acetaminophen for pain relief during pregnancy has been associated with a three times higher risk of ADHD in the child.

Researchers found that low but normal-range B12 levels in older adults are linked to slower cognitive processing and white matter damage in the brain. The findings suggest current B12 recommendations may be outdated.

The immune systems of cancer patients are highly disrupted, with those who have a higher number of immune cells in their blood having a better survival rate, finds a new study that uses a pioneering technique.

A phase 2 trial shows that olpasiran, an RNA-based therapy, reduces lipoprotein(a) [Lp(a)] levels by more than 95% in cardiovascular patients. Lp(a) is linked to inflammation, plaque buildup and heart disease risk.

Researchers at The Jackson Laboratory created an aging breast tissue atlas, revealing how genetic and molecular shifts may increase cancer risk. Changes in epithelial, immune and stromal cells create a tumor-friendly microenvironment.

A new blood test could replace the current invasive diagnostic method for Alzheimer's disease.

Flow cytometry (FC) is a powerful tool for multi-parametric cell characterization. In this article, we explore the advances improving the accuracy and efficiency of FC and opening up new research and clinical applications.

Researchers at Fred Hutch and MD Anderson discovered RNA Polymerase II on histone genes as a biomarker for cancer aggressiveness. Using CUTAC technology, they accurately predicted tumor severity and recurrence in meningioma and breast cancer.

A research team has identified changes in brain rhythms that indicate seizure activity in Alzheimer’s patients.