Biomarkers – News and Features

A study from UC San Diego discovered that the PHGDH gene, previously linked to Alzheimer’s as a biomarker, actually plays a causal role. The team identified a moonlighting function of PHGDH that disrupts gene regulation, contributing to Alzheimer’s.

Researchers at Ruhr University Bochum and betaSENSE identified a biomarker in spinal fluid that detects early-stage Parkinson’s disease with over 90% sensitivity and specificity. This offers a potential solution to early diagnosis.

Researchers have shown that their smart bandage, the iCares, can clear excess moisture from wounds while also analyzing them to provide real-time data about different biomarkers present in a person's system.

Having a larger waistline, high blood pressure and other risk factors that make up metabolic syndrome is associated with an increased risk of young-onset dementia, a new study has found.

Portal Bio’s microfluidic technology enhances drug discovery and cell engineering by enabling efficient, scalable molecular delivery for sensitive cell types.

Researchers propose that mind blanking, characterized by a lack of mental content, is a distinct cognitive state. Unlike mind wandering, which involves active thought flow, mind blanking features reduced brain activity and physiological changes.

A clinical trial involving nearly 300 older adults with amnestic mild cognitive impairment (aMCI) found that regular physical activity helped slow cognitive decline and reduced brain volume loss.

An experimental vaccine that blocks Alzheimer's-related tau protein buildup has generated a robust immune response in both mice and non-human primates, building on earlier research.

Phenotypic screening has re-emerged as a powerful strategy for identifying drugs based on their observable effects. Discover how phenotypic screening accelerates drug discovery, supports drug repurposing and enables novel therapeutic breakthroughs.

Microglia can be engineered to detect disease-specific brain changes – like amyloid plaques in Alzheimer’s disease – and deliver therapeutics exactly where needed.