Biomarkers – News and Features

News
Protein Mobility May Be a Key Driver of Decreased Cellular Function in Chronic Disease
A study identifies "proteolethargy," reduced protein mobility caused by oxidative stress, as a unifying mechanism in chronic diseases. The findings suggest that impaired protein movement disrupts cellular functions.

News
Long-Term Hormone Therapy Reveals Cardiovascular Risks in Trans Men
A study highlights significant body composition changes and increased cardiovascular risks in transgender men on testosterone therapy. Over six years, muscle volume rose by 21%, abdominal fat by 70%, and LDL cholesterol increased.

News
A “Somato-Visual” Biomarker Could Help Diagnose Psychosis
University of Rochester researchers discovered a brain connectivity biomarker in MRI scans that may predict psychosis before symptoms emerge. The biomarker offers potential for early diagnosis and personalized treatment.

News
Short-Term Menopausal Hormone Therapy Has No Lasting Cognitive Effects
Short-term menopausal hormone therapy (mHT) does not have long-term cognitive effects when given to women in early postmenopause, according to new research from Mayo Clinic scientists.

News
What Can Cancer Research Learn From Agricultural Pest Management?
Researchers explore how established agricultural pest management strategies could be adapted to address cancer therapy. The pioneering method opens new possibilities for controlling drug resistance and improving patient survival.

News
AI Immune Cell Analysis Predicts Breast Cancer Prognosis
Researchers at Karolinska Institutet tested 10 AI models for predicting triple-negative breast cancer outcomes by analyzing tumor-infiltrating lymphocytes. Eight models demonstrated good prognostic ability.

News
New Diagnostic Method Reduces Interference From Common Blood Proteins
University researchers have developed a novel method to uncover low-abundance proteins in plasma, revealing critical biomarkers for early disease detection. This approach uses small molecules to reduce interference from common proteins.

News
Beyond Cholesterol: Sphingolipids’ Role in Atherosclerosis Revealed
New research describes how sphingolipids can also contribute to arterial plaques and atherosclerosis, revealing a new side to cardiovascular disease.

Article
Advancing Mass Spectrometry Data Analysis Through Artificial Intelligence and Machine Learning
This article delves into MS data analysis and its associated challenges, how AI/ML can aid analyses and exciting potential future developments in the field, with specific applications to proteomics and metabolomics research.

News
Glutamine Metabolism Key to Healthy Red Blood Cell Development
A St. Jude study reveals how glutamine metabolism shifts during red blood cell maturation to prevent oxidative stress and support heme production. Disruptions in this process contribute to disorders like β-thalassemia and sickle cell disease.
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