Cell Signaling – News and Features

Microscopic command centres in our bodies called primary cilia – once thought irrelevant – could be hidden switches powering cancer growth and drug resistance.

Discover how epiproteomics unlocks new biomarkers and drives breakthroughs in diagnostics and drug development.

GIP receptor agonism and antagonism engage different mechanisms to decrease body weight and food intake. These new findings could pave the way for more targeted medication against obesity.

A critical imbalance in bile acids can trigger liver diseases, including cancer. Researchers have identified a key molecular switch that regulates bile, shedding light on treatment avenues.

Methyl eugenol (ME) possesses significant antioxidant, anticancer and neuroprotective properties, potentially beneficial against diseases linked to oxidative stress. However, it also presents serious risks, including liver toxicity.

Researchers are determining how mechanosensor proteins in bacteria function to identify suitable conditions for establishing multicellular biofilms.

Phenotypic screening has re-emerged as a powerful strategy for identifying drugs based on their observable effects. Discover how phenotypic screening accelerates drug discovery, supports drug repurposing and enables novel therapeutic breakthroughs.

A common pinworm medication may stop and reverse cancer growth in Merkel cell carcinoma, an aggressive form of skin cancer, according to research led by University of Arizona Cancer Center researchers.

Researchers have identified a novel strategy for treating an aggressive form of leukemia – reprogramming the cancer cells to induce differentiation.

A team from Fujita Health University developed a computational model to simulate the formation of protein condensates at synapses, revealing how proteins like CaMKII help organize memory structures in the brain.