Cell Signaling – News and Features

A discovery in cardiac regeneration offers ew hope for the treatment of ischemic heart failure. Published in npj Regenerative Medicine, the study reveals a novel approach to promoting cardiomyocyte proliferation.

Researchers at Washington University and Stanford developed a cannabinoid compound that provides pain relief without psychoactive effects. By targeting a hidden pocket in the CB1 receptor, the drug avoids addiction risks.

Scientists at VCU Massey Comprehensive Cancer Center have identified an innovative combination of treatment strategies that work collaboratively to effectively kill acute myeloid leukemia (AML) cells, a frequently incurable form of cancer.

The Gene Ontology Consortium has released a new resource mapping human gene functions using evolutionary modeling. The PAN-GO functionome integrates experimental data from humans and model organisms, enhancing biomedical research.

Researchers find four coordinated gene expression programs in immune cells from glioma tumors, including two that could lead to immunotherapy resistance.

A new study from researchers at the University of Leipzig Medical Center and collaborators, has discovered a rare but serious side effect of CAR T-cell therapy in a 63-year-old patient.

Researchers at NYU Langone Health have discovered a previously unknown brain circuit that helps the brain quickly determine whether something is important or background noise. The circuit rapidly links sensory input, memory and emotion.

A new review highlights SETDB1 as a key player in osteosarcoma, promoting tumor growth, immune evasion and therapy resistance. Blocking SETDB1 could enhance immunotherapy and chemotherapy effectiveness.

Researchers have identified how a genetic flaw in some lung cancers alters cancer cell metabolism to fuel the disease.

A new study reveals that modifying the CUL5 gene enhances CAR-T cell therapy for leukemia and lymphoma. This improves cell longevity and tumor-fighting power, reducing cancer relapse.