Cell Signaling – News and Features

Penn State researchers have created LivGels, a self-healing hydrogel that mimics extracellular matrix (ECM) properties, including strain-stiffening and mechanical adaptability.

A weekly injection of diabetes medication could replace painful daily hormone shots for patients with a rare form of lipodystrophy.

New tools enable researchers to remotely and non-invasively guide engineered cells around the body to kill cancer or repair damaged tissue.

Researchers revealed mitochondria's role in immune regulation through IL-10 production, controlled by mitochondrial complex III and ROS signaling pathways. Enhancing mitochondrial function could treat inflammatory diseases like lupus.

A UVA research team identified 35 blood metabolites linked to SIDS, including key markers like ornithine and sphingomyelins, which impact neural and respiratory development. These findings highlight biological pathways underlying SIDS.

The ability to alter protein binding can create tailored therapeutics with reduced side effects, sensitive diagnostic tools, targeted drug delivery and sustainable bioremediation.

A contact protein printing technique enables researchers to control the formation of villi in human gut models, making it possible to study key cellular processes and disease-associated changes.

UNC Lineberger researchers discovered a three-drug cocktail that enhances the production of T-memory stem cells (TSCMs) in CAR-T therapy, improving immune cell persistence and anti-tumor activity.

A study reveals a genetic signature of 177 genes shared across cancers that drives metastasis. This pan-cancer breakthrough identifies two key genes, SP1 and KLF5, influencing metastasis progression.

Targeting a protein called endocan and its related signaling pathway could be a promising new approach for treating glioblastoma.