Drug Kinetics – News and Features

Researchers believe the key to understanding neurodegenerative diseases may lie in understanding how cholesterol and other lipids move through cells and affect their communication.

Researchers at Johns Hopkins and the Chinese Academy of Sciences discovered that a mouse protein, STELLA, blocks the cancer-associated protein UHRF1, reversing epigenetic changes that promote tumor growth.

Ultrasound-directed microbubbles could be used to influence the behavior of cancer-fighting T cells, reinvigorating the anti-tumor response.

A collaborative team has developed a new method to program molecular self-assembly predictably. Researchers created versatile materials like "Malteser molecules," which could serve as highly specific sensors or drug delivery agents.

A collaborative team has created inhalable mucoadhesive protein nanoparticles inspired by mussel adhesive properties. These biocompatible particles enable targeted delivery of anticancer drugs to the lung cancer microenvironment.

The use of human liver microtissues (hLiMTs) cultured in a 384-well microplate system was explored as a predictive model for assessing drug-induced liver injury (DILI) with promising results.

The complex interactions of the tumor–immune–gut axis can shape responses to immunotherapy in ovarian cancer, emphasizing the importance of understanding the patient's microbiome.

This article explores how 4D printing uses biomaterials to create shape-shifting medical devices, adaptive tissue scaffolds and targeted drug delivery systems.

Targeting antidepressant medications to cells in the gut could not only be an effective treatment of mood disorders like depression and anxiety but may also cause fewer adverse side effects.

Using the microrobots, the team successfully delivered therapeutics that decreased the size of bladder tumors in mice.