Lab of the Future – News and Features

St. Jude researchers reveal that moderate levels of mitochondrial DNA mutations boost leukemia growth by increasing metabolic plasticity, while high mutation levels shut down tumor development.

The 1831 “mystery eruption” that caused global cooling and famines has been traced to the Zavaritskii volcano on Simushir Island in the Kuril Islands. Researchers matched ash in polar ice cores to the volcano’s deposits.

Researchers from the Karlsruhe Institute of Technology attending AutoPET, an international competition in medical image analysis, detail how algorithms can detect tumor lesions in positron emission tomography (PET) and computed tomography (CT).

Yale researchers discovered that an underactive mTOR pathway drives structural malformations in lissencephaly. They showed that activating the mTOR pathway prevents and reverses thickened cortical structures.

A new method using cell-type-specific epigenetic clocks measures biological aging in neurons, glia and liver cells, revealing rapid aging in Alzheimer's and liver diseases. This tool improves understanding of aging-related diseases.

Karlsruhe Institute of Technology researchers have investigated how steroid hormones are degraded in an electrochemical membrane reactor with carbon nanotube membranes.

UK researchers introduced SWEET, a biodegradable and sustainable e-textile made from Tencel, graphene and PEDOT:PSS. Tested for heart rate and temperature monitoring, SWEET proved reliable and eco-friendly.

The SIMPL2 platform, developed by University of Toronto researchers, simplifies and improves protein interaction measurement, crucial for understanding disease mechanisms and developing drug therapies.

Researchers identified a stress-induced microglial pathway that accelerates Alzheimer’s disease by releasing toxic lipids that harm neurons and synapses. Blocking this integrated stress response reversed Alzheimer’s symptoms in preclinical models.

A University of Queensland study shows no link between childhood exposure to fluoridated water and negative cognitive outcomes. Researchers assessed IQs of 357 participants aged 16–26 and found no adverse effects.