Light Microscopy – Multimedia

By collecting more light and better correcting for light distortion, water immersion capabilities can unlock advanced imaging potential for greater insight into cellular pathways and processes.

Discover a single confocal imaging reader able to replace up to five individual devices and perform a variety of analysis outcomes common in biofilm workflows, including biomass screening

The specificity of fluorescence microscopy allows researchers to accurately observe and analyze biological processes and structures quickly and easily, even when using thick or large samples. However, out-of-focus fluorescence increases background, reduces contrast and makes accurate image segmentation more challenging.

Scientists at Scripps Research have devised a method that may be able to shortcut one of the big steps in modern vaccine development.

This video, an honorable mention at the 2021 Nikon Small World in Motion Competition, shows the nervous system of a 7-day old chicken embryo, imaged using light sheet microscopy.

Studying tissue and organ biology is challenging, particularly in mammals, given sample accessibility and ethical concerns. However, the use of organoids alleviates these challenges, supporting researchers in exploring questions that previously could not have been investigated without them.

Water is a major component of all cell culture media and is, therefore, needed to prepare media, buffers and additives, as well as to serve many ancillary functions, such as heating, cooling, cleaning and rinsing.

Since the earliest microscopy efforts in the 1600s, cell imaging has significantly modernized and become a ubiquitous tool in cell biology laboratories. Here, we cover five key advances in cell microscopy to help you understand how the field is progressing.

In this list, discover more about the key RNA-seq techniques used in neuroscience, including the direction and contributions of single-cell RNA sequencing, patch-seq and fluorescence in situ sequencing.

Download this guide to gain insight into the key aspects of caring for your confocal microscope.