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Neurodegeneration – News and Features

Cigarette ends in an ashtray

Study Offers Fresh Perspective on Smoking-Related Variant "Mr. Big"

According to research, people with a certain version of the most well-known smoking-related variant to date, “Mr. Big”, are less sensitive to nicotine and have been shown to smoke more.
A collection of many different pills.
Industry Insight

Setting the Stage for Multipurpose Drugs

We spoke with Dr. Bryan Oronsky, chief development officer at EpicentRx, to discover more about the promise of multipurpose drugs and the potential of EpicentRx’s nibrozetone (RRx-001) for several conditions.
A dropper of CBD oil.

No Evidence That CBD Products Reduce Chronic Pain, Study Finds

A new study has concluded that there is no evidence that cannabidiol (CBD) products reduce chronic pain, suggesting that they are not value for money and even have the potential to harm health.
MRI images of brains.

Human Brains Are Getting Bigger – What Does That Mean for Dementia Risk?

Brain magnetic resonance imaging data obtained from participants recruited to the Framingham Heart Study (FHS) reveals a gradual increase in brain size, who might explain the reduced incidence of Alzheimer's disease.

Brain pH Changes Linked to Wide-Ranging Cognitive Issues

The International Brain pH Project Consortium unveils findings in a large-scale animal model study, indicating altered brain pH and lactate levels as a transdiagnostic endophenotype in neuropsychiatric disorders with cognitive impairment.
Neurons connecting.

New Research Identifies Key Driver of Myelination in the Brain

New research from scientists at the Wu Tsai Neurosciences Institute at Stanford University has identified a key driver of myelination, the formation of protective fatty sheaths around nerve fibers.
A woman smiling.

Smiling Unlocks Our Perception of Happiness

The study shows that even a brief weak grin makes faces appear more joyful. The pioneering experiment used electrical stimulation to spark smiles and was inspired by photographs made famous by Charles Darwin.
A person lies on their side unconscious

Early Intervention Post-Seizure May Prevent Long-Term Epilepsy

According to research, an experimental treatment can prevent long-term changes to neurons seen in epilepsy if provided within the first two days after the first seizure.
Cells labelled with bright green and blue dye.

Molecular Links Between ALS and FTLD Cognitive Disorders Exposed

Gene expression patterns in the brain’s motor and frontal cortex reveal many shared cellular and molecular similarities between ALS and FTLD that could be targeted for potential treatment.
A blastoid cell model system, with nuclei shown in blue.

Stem Cell Model Sheds Light on the Nuances of Early Development Gastrulation

Observing the molecular underpinnings of gastrulation would go a long way toward helping scientists prevent miscarriages and developmental disorders.