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Next-Generation Sequencing – News and Features

A butterfly next to a flower.
News

Butterfly and Moth Genomes Remain Mostly Unchanged Over Past 250 Million Years

Comparison of over 200 high-quality butterfly and moth genomes reveals key insights into their biology, evolution and diversification over the last 250 million years, as well as clues for conservation.
Laughter between an older and younger male.
News

Ancient DNA Reveals Down Syndrome in Historical Populations

A new study scoured ~10,000 ancient genomes in search of trisomies, such as Down Syndrome. Combined with archeological analyses, the data reveal how these infants were perceived in ancient societies.
A strand of DNA.
News

10 Polygenic Scores for Chronic Disorders Progress to the Clinic

By analyzing millions of small genetic differences, researchers can calculate a polygenic risk score for disease. Ten of these risk scores have been validated for clinical use.
Light breaks through the ocean's surface.
News

Researchers Catalogue Ocean Viruses That Can Capture Carbon

By combining genomic sequencing data with AI analysis, researchers are zeroing in on the ocean viruses that can capture carbon and help combat climate change.
A cow.
News

Bulls Offer Insight Into Male Fertility

Researchers have found genes in the reproductive organs of bulls that influence fertility. The findings can be transferred to humans, as these genes are also present in men.
A top-down photo of a jar of hard-boiled candies.
News

Does Sugar-Free Candy and Gum Give You Gas? It Could Be Your Microbiome

Researchers have identified changes to the gut microbiome that affect our ability to digest sorbitol – a key ingredient in sugar-free products.
An alarm clock.
News

New Epigenetic Clocks Predict Biological Age More Robustly

Investigators unveil a new form of epigenetic clock – a machine learning model designed to predict biological age from DNA structure. The novel model distinguishes between genetic differences that slow and accelerate aging.
Four men of different ancestries.
News

What Role Does Ancestry Play in Prostate Cancer Risk?

A recent study has uncovered insights into the prostate cancer risks of people from a variety of genetic ancestries.
High-Throughput Chromosome Conformation Capture technology allowed scientists to detect bacteriophage-host infection networks and how they varied between dry and wet soil.
News

Unraveling Soil Microbial Dynamics Through Phage-Host Interactions

High-Throughput Chromosome Conformation Capture technology allowed scientists to detect bacteriophage-host infection networks and how they varied between dry and wet soil.
Red and white and blue and white capsule drugs.
Industry Insight

Sourcing Chemistry From Inside Humans

In this interview, Dr. Jason Park, co-founder and CEO of Empress Therapeutics, tells us more about the Chemilogics platform and the benefits this approach to drug discovery can offer.
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