NMR Spectroscopy – News and Features

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To the Depths of Drug Discovery
Natural products have been harnessed for their therapeutic properties throughout the history of medicine. Land-dwelling – or terrestrial organisms – have naturally dominated the focus of scientists wanting to access nature’s pharmacopeia. But an untapped resource of natural products, large in size and potential, was close by – we just couldn’t access it.

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Supercomputer Helps Understand the Physics of Thought
A supercomputer has enabled multi-million atom models of the proteins involved in synaptic vesicle fusion, revealing insights into the biophysics of thought.

News
How Two Types of Tau Proteins Mix Together To Form Tangles
A new study has revealed how two types of tau proteins mix together to form neurofibrillary tangles in the brain, a hallmark of Alzheimer's disease.

News
Protein Structures To Aid Rational Drug Design
The structure of the C1 domain of protein kinase C – a protein implicated in many diseases including AIDS, Alzheimer's and cancer – has been solved, aiding rational drug design efforts.

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Seeing Inside the MOF "Sardine Can"
Spectroscopy with two differently polarized types of infrared light, has led to the first measurement of both guest-guest and guest-host interactions of metal-organic frameworks in real-time.

News
Protein Pump Helps Bacteria To Become Resistant to Antibiotics
Chemists have discovered the structure of a protein that can pump toxic molecules out of bacterial cells. Proteins similar to this one are believed to help bacteria become resistant to multiple antibiotics.

Article
Metabolomics-Based Blood Test Could Enable Earlier Detection of Cancer
Dr. James Larkin discusses the benefits of biofluid metabolomics and how an NMR-based approach could help to improve the way that cancer is detected and monitored in patients with nonspecific symptoms.

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Atomic Absorption Spectroscopy, Principles and Applications
In this article, we explore atomic absorption spectroscopy, what is is, how it works, strengths and limitations and the areas in which the technique finds utility.

News
Targeting SARS-CoV-2's Tangled Strands of RNA
The complex shapes that RNA takes on as it folds upon itself could have untapped therapeutic potential in the fight against COVID-19. Researchers have identified chemical compounds that can latch onto these 3D structures and block the virus’s ability to replicate.

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NMR Spectroscopy Principles, Interpreting an NMR Spectrum and Common Problems
Nuclear magnetic resonance (NMR) spectroscopy is a physicochemical technique used to obtain structural information about molecules. In this article, we consider how it works, what it tells you and where it is used.
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