NMR Spectroscopy – News and Features

An important step in programmed cell death is the binding of a protein (called cytochrome c) to the membrane of mitochondria. Scientists have now discovered that cytochrome c is partly unfolded during this important step and they can pinpoint which parts of the protein are folded or unfolded.

Researchers have shown how changes in an environment-sensing protein enable bacteria to survive in different habitats, from the human gut to deep-sea hydrothermal vents.

A mutational change in a chromatin-regulating enzyme called histone-lysine N-methyltransferase (NSD3) has been shown to promote a common type of lung cancer.

A new study has shone light on the molecular steps behind the spread of prion diseases, a group of incurable brain conditions that have puzzled researchers for decades.

p53 is a natural anticancer protein, sometimes called “guardian of the genome” due to its ability to repair DNA damage or destroy cancer cells. A study exploring the interaction between p53 and the green tea compound epigallocatechin gallate now points to a new therapeutic target.

Scientists report major discoveries on how a class of molecules called polyampholytes can safely freeze biological materials.

People want their coffee to be both satisfying and reasonably priced, therefore, roasters typically blend arabica and robusta coffee beans. But, some use more of the cheaper robusta than they acknowledge. Now, researchers have developed a new way to assess exactly what’s in that cup.

Over the past decade, fragment-based drug discovery has garnered increasing interest among drug discovery experts and has established itself as a key approach within the field – acting as an alternative starting point for the discovery of high-quality lead candidates. This article discusses the evolution of FBDD, highlights key drug discoveries, and explores the advantages and challenges of harnessing this approach

The diverse nature of the metabolome continually challenges researchers and creates a colorful array of opinions on which is the most comprehensive and precise approach, explored in this article.

Research alliance has observed the RNA folding structures of the SARS-CoV2 genome with which the virus controls the infection process.