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Pharmacovigilance – Multimedia

Eliminating Problems in Drug Development: Understanding the Role of Drug Metabolism content piece image
Video

Eliminating Problems in Drug Development: Understanding the Role of Drug Metabolism

This talk will discuss processes for the metabolism of a drug, referred to as ADME (Absorption, Distribution, Metabolism, Excretion), and the safety testing to provide requisite information to move a drug through IND and into clinical trials. Prior to marketing a new drug and actually prior to administering a candidate drug to humans in clinical trials, it is important to ensure that drug will not only be effective in the therapeutic manner prescribed, but also be safe and not bring any undo harm to patients.
Shape-Morphing Microrobots Deliver Drugs to Cancer Cells content piece image
Video

Shape-Morphing Microrobots Deliver Drugs to Cancer Cells

Delivering drugs directly to cancer cells could help reduce the unpleasant side effects of chemotherapy.
The Important Role of UDP Glucuronosyltransferases in Drug Metabolism and Drug–Drug Interactions content piece image
Video

The Important Role of UDP Glucuronosyltransferases in Drug Metabolism and Drug–Drug Interactions

The importance of glucuronidation for metabolism of xenobiotics in humans is illustrated by the abundance and broad tissue distribution of the enzymes, the diversity of substrates and reactions catalyzed, as well as a number of distinctive UGT enzymes and their genetic polymorphisms.
Looking Deeper: Imaging and Analysis of Advanced 3D Cellular Models  content piece image
eBook

Looking Deeper: Imaging and Analysis of Advanced 3D Cellular Models

By recreating many of the cell-cell and cell-matrix interactions found in native tissues, spheroids and organoids provide more physiologically accurate models of disease and development than traditional 2D cultures.
Drug–Target Binding: Recent Research Developments content piece image
Listicle

Drug–Target Binding: Recent Research Developments

Being able to accurately predict drug–target interactions (DTIs) and drug–target binding affinity (DTBA) is crucial in early drug development and during drug repurposing endeavors. Here, we look at some recent research developments in this space.
COVID-19: Vaccines, Pregnancy, Menstruation, Breastfeeding and Fertility content piece image
Video

COVID-19: Vaccines, Pregnancy, Menstruation, Breastfeeding and Fertility

What is the guidance for vaccination of women with breastfeeding infants, women who are pregnant or planning to get pregnant and women who are menstruating? What about vaccines and fertility? WHO’s Dr Soumya Swaminathan explains in Science in 5.
How Stem Cells Are Shaping Drug Discovery content piece image
Listicle

How Stem Cells Are Shaping Drug Discovery

Stem cells are increasingly being used in new and innovative ways to improve the drug discovery process – spanning academia, biotech start-ups and large pharmaceutical companies.
Key Developments in Cancer Immunotherapy Over the Last Decade content piece image
Listicle

Key Developments in Cancer Immunotherapy Over the Last Decade

Download this list to explore current immunotherapeutic strategies, recent regulatory approvals and the future of cancer therapy.
Key Techniques in Cell Therapy Quality Control content piece image
Listicle

Key Techniques in Cell Therapy Quality Control

Download this list to discover more about some of the latest key techniques in cell therapy quality control.
Why COVID-19 Vaccine Side Effects May Feel Worse After the Second Dose content piece image
Video

Why COVID-19 Vaccine Side Effects May Feel Worse After the Second Dose

This video explores why COVID-19 vaccines cause short-term side effects, and why these may feel worse after the second dose of the vaccine.
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