Pharmacovigilance – News and Features

Could energy-dispersive X-ray fluorescence spectrometers help improve our understanding of environmental health? Discover how innovative XRF techniques are helping to create a cleaner, healthier world.

A new drug, RI-AG03, developed by researchers at the University of Southampton, targets two critical regions of the tau protein linked to Alzheimer's disease. Early tests demonstrated the drug's effectiveness in reducing tau aggregation.

UCLA researchers developed a non-invasive imaging method using 89Zr-TLX250 to detect clear-cell renal cell carcinoma. This technique demonstrated high sensitivity (85.5%) and specificity (87.0%), effectively identifying cancer in small renal masses.

Frequent use of doxycycline – a post-exposure prophylaxis for STIs – increases antibiotic resistance in the gut microbiome.

A study of European green and blue tattoo inks revealed that 9 out of 10 inks violated EU regulations by containing unlisted and banned substances. The researchers stress the need for better manufacturing standards.

A therapy showing promise to help control tuberculosis (TB) does not interfere with combined antiretroviral therapy (cART). This may advance TB therapy for those who are immunocompromised as a result of HIV.

Researchers found that time-restricted eating–also known as intermittent fasting–could offer significant health benefits to adults with metabolic syndrome. Patients saw improvements in several markers of blood sugar regulation and metabolic function.

Researchers have made a significant step towards enabling women with epilepsy safer access to a common and highly effective anti-seizure medication.

Individuals fully vaccinated against COVID-19 have a significantly lower risk of developing more severe cardiovascular conditions linked to COVID-19 infection, yet some cardiovascular effects have been seen after individual doses of the vaccine.

We spoke to Andrew Doig, professor of biochemistry at the University of Manchester, to find out more about the evolving landscape of Alzheimer's treatments.