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Pharmacovigilance – News and Features

A plastic model of a bisected human brain.

New Approach to Provoking Seizures Helps Guide Epilepsy Surgery

Researchers have developed a new method for triggering and imaging seizures in epilepsy patients, offering physicians the ability to collect real-time data to tailor epilepsy surgery.
Multicolored virus icons.

Study Identifies Leads From Nature for HIV Drug Development

A team of University of Michigan researchers has successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity.
A scientist with gloved hands using tweezers to pick up a sample of a dried bean from a selection of pots of pulses.

Chromatography Techniques Shed Light on the Pervasive Toxins in Our Food Supply

Researchers shed light on the pervasive presence of natural toxins, environmental pollutants and food-processing contaminants in our food and review the techniques used to detect them that are gaining popularity.
A gloved hand holds a syringe filled with red liquid.

CAR T-Cell Therapy Shows Activity in Subgroup of Brain Tumor Patients

A CAR T-cell therapy for glioblastoma has demonstrated promising clinical activity in a Phase 1 trial.
A digital illustration of a brain emitting multi-colored strands.

Experimental Drug Shows Early Promise for Rare, Incurable Brain Tumors

A study of five early-stage clinical trials has found that an experimental drug may have favorable results for a rare and incurable type of brain tumor, for which there are very few treatment options.
An image of a brain with electrical sparks coming from it.

VR and Electrical Brain Stimulation Show Promise in Trial for PTSD

Combining transcranial stimulation with virtual reality exposure significantly reduced PTSD symptoms in veterans.
Two syringes filled with pale yellow liquid.

Nanoparticle Discovery Could Make Vaccines More Powerful

A type of nanoparticle can activate a powerful immune response, showing promise for use as both the vaccine delivery system and as an adjuvant.
A digital anatomical illustration of the human brain.

Stimulating Brain Waves May Protect Against “Chemobrain”

A method to stimulate gamma brain waves could pave the way for a non-invasive treatment for so-called “chemobrain”, according to a new study from MIT researchers.
A close up of a broccoli and its leaves.

Broccoli Chemical Can Reduce Blood Clot Risk

A compound derived from broccoli could be used to treat stroke, as it makes the current clot-busting medication more effective.
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Improved Persistent Organic Pollutants Analysis for a Safer Global Environment

Persistent organic pollutants (POPs) are toxic chemicals that threaten human health and cause environmental deterioration. This article highlights the potential of trapped ion mobility spectrometry (TIMS) for improved POPs analysis.