Pharmacovigilance – News and Features

A drug effective in treating breast cancer shows new promise in addressing breast cancer with brain metastases.

The prestigious journal Science Translational Medicine has published a study by researchers from the Institute of Biology Leiden (IBL) on a potent new antibiotic that can overcome resistance.

A study in nonhuman primates found a dramatic decrease in levels of the monkey form of HIV after one shot of Therapeutic Interfering Particles (TIPs). The study suggests that one TIP shot could prevent a person living with HIV from passing on the virus.

Researchers have successfully created 3D printed lungs, designed to study respiratory infections and test new drugs.

Patients in England with severe beta-thalassaemia will be amongst the first in Europe to benefit from one-time gene therapy exagamglogene autotemcel (“exa-cel”, also called Casgevy and made by Vertex).

Nearly a quarter of children with recurrent wheezing have “silent” lung infections without symptoms, new research from the School of Medicine reveals. That finding could have big effects on how the condition is treated.

Researchers have developed a drug that shows promise in animal models of multiple sclerosis (MS). If successful in humans, the drug could help to replace the protective insulation around nerve cells lost because of the disease.

Increased rates of stillborn births were seen among people who lived near areas where pesticides were used during their first trimester of pregnancy or pre-conception.

Scientists have taken a fresh approach to finding a way to target neuroblastoma, the most common solid tumor of infancy. Their novel gene target could offer hope for finding alternative treatments with fewer long-term side effects.

Researchers have found evidence of higher levels of the plastic chemical bisphenol A (BPA) in pregnant mothers who gave birth to sons with autism.