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Screening Strategies in Drug Discovery – News and Features

Gloved hand holding a white drug capsule near test tubes with blue liquid, symbolizing drug discovery research.
Article

Improving Efficiency in Drug Discovery and Development

This article explores methods to enhance efficiency in the drug discovery and development pipeline, focusing on optimizing processes and exploring innovations that could streamline the path from research to approval.
Droplet of liquid coming out of pipette tip above an assay well
News

Evaluating Thousands of Compounds On Cellular Metabolism

Researchers can test the effects of more than 1,500 compounds on cell metabolism in parallel. Their analysis also led to the discovery of previously unknown mechanisms for known drugs.
A drug capsule filled with small beads, with cells in the background.
Article

The Impact of Functional Genomics in Drug Discovery

Functional genomics can help deconvolute the link between genotype and phenotype in disease, revealing new drug targets and progressing understanding of existing drugs.
Illustration of a syringe dispersing broadly neutralizing antibodies targeting viral structures.
Article

How Broadly Neutralizing Antibodies Are Driving Next-Gen Vaccines

This article explores how broadly neutralizing antibodies are being researched, not only for their potential in the prevention of HIV, but also for other rapidly mutating viruses such as influenza and SARS-CoV-2.
An illustration of a wavy, green, plastic-like material, lit up against a black background. The material has small light dots across its surface,representing a data stream.
Article

How Is AI Accelerating the Discovery of New Materials?

With the advent of machine learning and artificial intelligence, materials science could be poised to take its next big leap in efficiency since the introduction of computational chemistry.
An illustration of a drug capsule on a computer chip.
Article

How Is AI Being Used in Drug Discovery?

This article provides examples of how AI is helping to shape drug discovery, from drug design through to clinical trials.
Microplate held up by a gloved hand with a zoomed in circle showing an image of the microtissue culture in one well.
Article

Prediction of Liver Toxicity Revolutionized in Largest 3D In Vitro Benchmarking Study

The use of human liver microtissues (hLiMTs) cultured in a 384-well microplate system was explored as a predictive model for assessing drug-induced liver injury (DILI) with promising results.
A image of a pill.
Industry Insight

Research Partnership Aims To Advance Fragment-Based Cancer Drug Discovery

Cancer Research Horizons and Diamond Light Source aim to strengthen their partnership, combining their expertise and resources to bring new cancer treatments to patients.
Cancer cells.
News

Cancer Cells’ “Eating” Ability Could Inform Treatment

Scientists discovered how cancer cells migrate by digesting the surrounding tissue matrix, enabling them to spread. A molecule called a2b1 integrin was identified as a key driver of this process. Blocking a2b1 integrin reduced cancer cell migration.
Immunotherapy molecules fighting a cancer cell.
News

Virtual Drug Screening Identifies Candidates for Cancer Immunotherapy

Researchers at Weill Cornell used virtual screening to find small molecules targeting cancer checkpoints, showing promise as alternatives to monoclonal antibody treatments. The study identified compounds MG-T-19 and MG-V-53.
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