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Screening Strategies in Drug Discovery – News and Features

Different medications on a red background.
News

Could Existing Drugs Treat "Lincoln's Ataxia"?

Researchers have developed a new method to determine if FDA-approved drugs could be repurposed or improved to help patients with a rare disease of the nervous system, Spinocerebellar ataxia type 5.
Gloved hand holding a slightly open blood agar Petri dish of bacteria up to a computer screen displaying a protein structure.
Article

Understanding Structural Biology, Its Applications and Creating a Molecular Model

In this article, we consider what structural biology tells us and the techniques used to investigate it, the role of computation and how techniques can be used together to answer questions in a range of application areas.
Three boxes with chemical structures coming from them.
News

New Method for Targeted Design of Molecules With AI

Researchers have combined various artificial intelligence methods to enable the targeted design of molecules with specific properties,
Gloved hands hold an agar dish and a cotton swab. In the background other agar dishes and a test tube rack can be seen.
Article

Cell Culture – Good Practice and Advanced Methods

This article will explore the importance of cell culture quality control and highlight recent developments in this area.
Illustration of a cell culture plate with various organoids linking to the area of the human body they are from.
Article

An Introduction to Organoids, Organoid Creation, Culture and Applications

Organoids have revolutionized biological and medical research and proven to be excellent substitutes for animal models in preclinical studies. Here, we discuss what organoids are and how they have been developed over the years to become popular research tools.
Results of a cDNA microarray, reflecting the gene expression differences between two different tissues.
Industry Insight

Innovations and Versatility in Modern Microarray Technology

In this interview, CEO of Arrayjet Dr. Iain McWilliam discusses advancements in modern microarray technology and the benefits that these tools can provide for high-throughput screening.
A pipette dispenses cell culture media into a microwell plate.
Article

Advances in Cell Line Development To Enhance Biotherapeutic Production

This article will discuss the development of cell lines for biotherapeutic production and will touch on key considerations, such as future manufacturability.
A man wearing glasses with black frames looks through a screen with a digital overlay.
Article

Towards the Lab of the Future

In this article, we look at the barriers preventing more widespread adoption of automation and digitization, and the opportunities they could bring.
Baker's yeast.
Article

Making Cancer Medicines With Microbes

For oncology, plant-based anti-cancer drugs have proven instrumental in the fight against a disease that claims approximately 609,360 lives in the United States alone. But their demand far outweighs their supply. Can yeast help?
White and red pill cut in half showing a silver ball and stick molecular structure inside.
Article

Target Identification and Validation in Drug Development

This article will highlight the properties of an attractive drug target, outline the approaches used to identify targets and discuss the key steps involved in target validation.
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