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Spatial Biology – News and Features

Cancer cells.
News

The Role of Vitamin B6 in Pancreatic Cancer

In a recent publication in the journal Cancer Discovery, Mehla details the role of vitamin B6 in healthy people and when pancreatic cancer is present.
A bright field image of a testicular organoid created from mouse embryos and incubated in a dish for 14 days.
News

“Testes in a Dish” Advance Male Fertility Research

The artificial testicles will contribute to the advancement of research in male fertility and sexual development disorders, and are expected to facilitate the eventual production of sperm in the laboratory.
Breast cancer cells, with the nucleus shown in blue and microfibers and stress fibers shown in red and green.
News

Molecule That Reactivates Dormant Cancer Cells Discovered

A molecule that can reactivate dormant breast cancer cells and nudge them toward metastasis has been identified. The researchers also showed that inhibiting this molecule can reduce metastases.
Human cells.
Article

The Need To Scale Single-Cell Functional Studies

Kathrin Herbst reviews the pros and cons of various single-cell technologies and discusses the need to move to functional readouts in the future.
Cancer cells.
News

New Study Reveals Targetable Mechanism in Pancreatic Cancer Metastasis

A research paper published in Nature Cancer details new insights into the role of efferocytosis – the burying of dead cells – in pancreatic cancer that spreads to the liver.
Cancer cells.
News

Targeting Chemotherapy-Resistant Cells

Each round of chemotherapy kills the majority of cancer cells, while a small population of them survives through treatment. These cells are typically more resistant for the next cycle of therapy and can thus regrow.
Stem cells.
News

Using Stem Cells To Enhance Cancer Immunotherapy Without Genetic Modification

A joint research team has used stem cells to generate human immune cells for application in cancer immunotherapy. This breakthrough platform is expected to significantly enhance cancer-targeting efficacy.
Double helix structure of DNA.
News

Single-Cell Analysis Explains Cancer Patients' Sensitivity to Epigenetic Drugs

Researchers described the effects of chemotherapy at the single cell resolution in the bone marrow of Myelodysplastic Syndrome patients. The results help better understand which cellular populations are more sensitive to an epigenetic drug.
Cancer cells adhered to a surface.
Article

Cell-to-Cell Communication in Cancer

We typically think of a cancerous tumor as a bunch of abnormal cells gone rogue, but the situation is more complicated. This article will explore cell-to-cell communication’s role in cancer development, its influence on metastasis and how research is expanding our knowledge of the disease.
A woman holding her pregnant bump.
News

Genetic and Cellular Changes Pinpointed in Placenta Accreta

A new study may change the way clinicians and scientists understand, diagnose and treat placenta accreta spectrum disorder, a serious condition in which the placenta fails to separate from the uterus at birth.
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