Spatial Biology – News and Features

The tumor microenvironment is a harsh environment where metabolic adaptations are key. In this article, we explore how the metabolic constraints of the TME influence cancer and immune cells and dive into the metabolic cross-talk between them.

Mapping a tumor's cellular neighborhood in three dimensions could identify potential targets for personalized cancer therapy.

Researchers have discovered that expansion of mutant blood cells, a phenomenon linked to ageing, can be found in cancerous tumours, and this is associated with worse outcomes for patients.

A team of researchers from the University of Chicago, has identified a novel oncometabolite that accumulates in tumors and impairs immune cells’ ability to fight cancer.

New research demonstrates the role of the Galectin-1 protein in the nucleus of the cells surrounding the tumor-fibroblasts contributing to their activation.

In this article, Technology Networks spoke with Dr. Jack Hoppin and Dr. John Babich from Ratio Therapeutics to learn more about the recent radiopharmaceutical revolution.

A longitudinal atlas of neuroblastoma, a common and deadly childhood cancer, could uncover the precise molecular mechanisms underlying why and how certain treatments eventually become ineffective.

The detection of peripheral neural stem cells could transform the treatment of Parkinson's disease and spinal cord injuries.

By mapping the subcellular architecture of tumor cells, researchers can better understand how mutations cause cancer.

Researchers from Singapore, South Korea, Japan, Thailand and India have assembled the world's first Asian Immune Diversity Atlas – a multi-national survey of human blood at single-cell resolution.