The Immune System – Multimedia

Obesity Leads to Lymphatic Wall Remodeling and Systemic and Tissue-Associated Inflammation in Zucker Rats

Inflammatory bowel diseases (IBD) often present in adolescence and affect >1.4 million persons in the US. Environmental exposures, notably air pollution and weather, have been suggested to contribute to IBD disease activity. Our goal was to evaluate relationships between environmental exposures and the prevalence and disease activity of pediatric IBD using novel data sources that take into account geographic location.

Patients with partial deficiency of recombination-activating genes 1 or 2 (RAG1/2) can present with a wide spectrum of primary immunodeficiencies including combined immunodeficiency with granuloma and/or autoimmunity (CID-G/AI). Prior case reports have highlighted alterations in B and T cell compartments; however comprehensive characterization of these cell populations with focus on autoreactive-prone subsets has not been reported.

Discover how scientists are harnessing the body's own immune system to fight cancer, and how they are using quantitative pathology solutions from PerkinElmer to better understanding the interactions between the immune system and cancer, and to identify biomarkers for translational research.

Our immune system plays a vital role in protecting us from illness and infection by fighting off invaders to our body… but when our own cells are the source of the problem, as in cancer, what then?

In January 2016 a number of countries in South East Europe started vaccinating cattle against lumpy skin disease. As the programme has progressed the number of outbreaks has fallen and by the end of 2017 the outbreaks had been contained.

This list highlights 8 of the biggest milestones within the field of cancer research since the year 2000.

Download this guide to learn essential tips to maintain an aseptic environment and prevent cell culture contamination.

Here are 10 tips to help you optimize your clinical flow cytometry experiments and ensure consistent results.

CAR T-cell therapy, like all forms of cancer immunotherapy, seeks to sharpen and strengthen the immune system’s inherent cancer-fighting powers. It involves treating patients with modified versions of their own immune system T cells.